abstract：:The applicability of a computer model, which relates the transmural mechanical distribution in the left ventricle (LV) to its global function at different loading conditions, was evaluated in patients with normal to near normal LV function undergoing cardiac catheterization. Left ventriculography and measurements of a...

journal_title：Annals of biomedical engineering

authors： Abboud L,Beyar R,Battler A,Rat M,Cohen A,Sideman S

更新日期：1990-01-01 00:00:00

abstract：:Based on mathematical expressions governing the electric field, the extracellular potentials generated by a single active fiber in a restricted circular cylindrical volume conductor are evaluated. This paper examines the effect of the extent of the volume conductor, with radius b, on the extracellular potentials at di...

journal_title：Annals of biomedical engineering

authors： Trayanova N,Henriquez CS,Plonsey R

更新日期：1990-01-01 00:00:00

abstract：:The pulmonary microvasculature offers a heterogeneous barrier to the motion of large solutes as they pass between blood and lymph. While this barrier has been approximated by a few discrete pathways or by statistical ensembles of many pathways, these descriptions only partly capture the structural and functional prope...

journal_title：Annals of biomedical engineering

authors： McNamee JE

更新日期：1990-01-01 00:00:00

abstract：:To better understand oxygen utilization by the retina, a mathematical model of oxygen diffusion and consumption in the cat outer, avascular retina was developed by analyzing previously recorded profiles of oxygen tension (PO2) as a function of retinal depth. Simple diffusion modelling of the oxygen distribution throug...

journal_title：Annals of biomedical engineering

authors： Haugh LM,Linsenmeier RA,Goldstick TK

更新日期：1990-01-01 00:00:00

abstract：:The optimal means of electrically stimulating a skeletal muscle to contract around a fluid-filled pouch (i.e., a skeletal muscle ventricle [SMV]) has not been determined. A SMV was made from the latissimus dorsi muscle in five dogs and the rectus abdominis muscle in five dogs, and each SMV was electrically stimulated ...

journal_title：Annals of biomedical engineering

authors： Badylak SF,Wessale JE,Geddes LA,Janas W

更新日期：1990-01-01 00:00:00

abstract：:Of the many models of peripheral nerve in the literature, essentially all have relied on experimentally derived values for the anisotropic resistivity of the nerve bundle interstitial space. This paper is a comprehensive mathematical analysis of the most referenced experiment for the longitudinal and radial resistivit...

journal_title：Annals of biomedical engineering

authors： Altman KW,Plonsey R

更新日期：1989-01-01 00:00:00

abstract：:A lumped parameter compartmental model for the nonsteady flow of the cerebrovascular fluid is constructed. The model assumes constant resistances that relate fluid flux to pressure gradients, and compliances between compartments that relate fluid accumulation to rate of pressure changes. Resistances are evaluated by u...

journal_title：Annals of biomedical engineering

authors： Sorek S,Bear J,Karni Z

更新日期：1989-01-01 00:00:00

abstract：:The purpose of this study is to measure the transmural pressure-cross sectional area relation of micro tubes (240 microns diameter) and to compare the measured perfusion pressure-flow relation with the pressure-flow relation calculated from the experimental pressure-cross sectional area relation. The microtubes are ma...

journal_title：Annals of biomedical engineering

authors： Sipkema P,Westerhof N

更新日期：1989-01-01 00:00:00

abstract：:The effects of facet wiring procedure commonly used for stabilizing cervical spines after laminectomy or bilateral facet dislocation on the motion behavior of whole cervical spines are investigated using a Selspot II system. A fresh human ligamentous intact specimen was potted at T1/T2 vertebra and clinically relevant...

journal_title：Annals of biomedical engineering

authors： Goel VK,Clark CR,Harris KG,Kim YE,Schulte KR

更新日期：1989-01-01 00:00:00

abstract：:Impedance cardiography has not achieved popularity in the Intensive Care Unit (ICU) to date probably because of the limitations in technique and interpretation associated with the altered physiology of critically ill patients, and also because of interference from other machinery in the ICU. The current climate of que...

journal_title：Annals of biomedical engineering

authors： Fuller H,Raskob G,ter Keurs H,Hull R

更新日期：1989-01-01 00:00:00

abstract：:The extent to which sensorineural systems such as the auditory system are nonlinear depends on the type of stimulus that is used, and the part of the system from which recordings are made. An estimate of the first-order Wiener kernel of the evoked response from the inferior colliculus to amplitude-modulated tones and ...

journal_title：Annals of biomedical engineering

authors： Møller AR,Angelo RM

更新日期：1988-01-01 00:00:00

abstract：:The function of a chamber depends on its hydrodynamic properties: isometric pressures it can exert in the operating range of distensions, compliances in the operating range of distensions, and wall-displacement resistances in the operating range of distensions. Wall-displacement resistance is the departure of pressure...

journal_title：Annals of biomedical engineering

authors： Regen DM

更新日期：1988-01-01 00:00:00

abstract：:High energy laser has emerged to be an important surgical tool in medical technology. However, the application of laser energy to drill or cut a bone is still in an experimental state. In order to estimate the adequacy of laser heating of bone surface and at the same time minimize the damage to the bone tissue, we dev...

journal_title：Annals of biomedical engineering

authors： Chen II,Saha S

更新日期：1987-01-01 00:00:00

abstract：:We have studied the interaction of high frequency jet ventilation with cardiovascular pressures and flows. Results in dogs show that the amplitude of all intrathoracic pressures and flows fluctuate with a frequency equal to the difference between the heart rate and ventilator rate. The magnitude of this amplitude vari...

journal_title：Annals of biomedical engineering

authors： Mitzner W,Gioia F,Weinmann GG,Robotham JL,Ehrlich W

更新日期：1987-01-01 00:00:00

abstract：:Left ventricular (LV) diastolic filling is limited by the constraining effects exerted by the pericardium (PE) and the lung/chest wall. The aim of the present study was to assess the validity of various estimates of external cardiac constraint, compared to pericardial surface pressure (Ppe) measured lateral to the LV ...

journal_title：Annals of biomedical engineering

authors： Kingma I,Smiseth OA,Frais MA,Smith ER,Tyberg JV

更新日期：1987-01-01 00:00:00

abstract：:This is a personal historical essay on meanderings through the jungle of the microcirculatory swamp. Because one pretends that the wandering was purposefully exploratory, a few guideposts are placed at positions where one could discern blaze-marks from earlier wanderers, and the path cut a little wider along some of t...

journal_title：Annals of biomedical engineering

authors： Bassingthwaighte JB

更新日期：1987-01-01 00:00:00

abstract：:Double-exposure holographic interferometry is a contactless whole-field method. Dimensional changes are visualized as a series of interference fringes overlaid on the holographic image of the femur, where each fringe represents 0.316 micron (half the wavelength of the laser light) of motion. Interferograms for intact ...

journal_title：Annals of biomedical engineering

authors： Ovryn B,Manley MT,Stern LS

更新日期：1987-01-01 00:00:00

abstract：:A nonintrusive method for the visualization of pulsatile flow velocity profiles is described. The method is based on the use of a photochromic dye that is added to the fluid being studied and a nitrogen laser which excites the dye producing a marker "line" whose movement can be photographed. A microcomputer is used as...

journal_title：Annals of biomedical engineering

authors： Poots K,Cobbold RS,Johnston KW,Appugliese R,Kassam M,Zuech PE,Hummel RL

更新日期：1986-01-01 00:00:00

abstract：:Polycrystalline silicon (poly-Si) micromechanical structures can be made by selectively etching an underlying sacrificial oxide layer. Advantages of this micromachining technique are its simplicity and compatibility with conventional integrated-circuit processing. Compressive internal stress in poly-Si films constrain...

journal_title：Annals of biomedical engineering

authors： Howe RT

更新日期：1986-01-01 00:00:00

abstract：:The nonlinear diffusion-reaction equations describing the nonequilibrium transport of CO2 through flat layers of complex but homogeneous aqueous media were solved by an approximate analytical method called the "Combined Damköhler Number" (CDN) technique. Unlike other approximate analytical solutions, the CDN technique...

journal_title：Annals of biomedical engineering

authors： Hoofd LJ,Tong RR,Stroeve P

更新日期：1986-01-01 00:00:00

abstract：:A computer-controlled optical electromechanical biaxial test system was employed to study the mechanical response of excised sheets of canine visceral pleura. Three classes of tests were performed: uniform biaxial stretching tests and tests in which the specimen was cyclically stretched along one axis while either the...

journal_title：Annals of biomedical engineering

authors： Humphrey JD,Vawter DL,Vito RP

更新日期：1986-01-01 00:00:00

abstract：:The effects of training on a person's ability to perceive, interpret and utilize information presented via the tactile sense were examined by using a dual-channel electrocutaneous tracking approach. The electrocutaneous code studied was linear pulse rate encoding of information. The stimulus had a pulse width of 200 m...

journal_title：Annals of biomedical engineering

authors： Szeto AY,Chung YM

更新日期：1986-01-01 00:00:00

abstract：:Phospholipids have been identified by thin-layer chromatography in appreciable quantities in pericardial fluid taken from 12 dogs and found to include sphingomyelin and phosphatidylcholines, -ethanolamines, -inositols and -serines--the cholines predominating. The extracts, the synthetic surfactants and a mixture of sy...

journal_title：Annals of biomedical engineering

authors： Hills BA,Butler BD

更新日期：1985-01-01 00:00:00

abstract：:Some investigators have attempted to estimate the Reynolds shear stress on the basis of a single component of velocity. The purpose of this investigation is to determine the validity of such estimates in a complex flow field, such as occurs in the cardiovascular system in the region of the aortic valve. Turbulent velo...

journal_title：Annals of biomedical engineering

authors： Walburn FJ,Sabbah HN,Stein PD

更新日期：1985-01-01 00:00:00

abstract：:The cerebral blood flow (CBF) response to changes in perfusion pressure mediated through decreases in arterial pressure, increases in cerebrospinal fluid (CSF) pressure and increases in jugular venous pressure was studied in anesthetized dogs. A preparation was developed in which each of the three relevant pressures c...

journal_title：Annals of biomedical engineering

authors： Wagner EM,Traystman RJ

更新日期：1985-01-01 00:00:00

abstract：:Vascular smooth muscle mechanics have been studied in vitro in cylindrical segments of dog carotid artery, human internal mammary artery, and human saphenous vein. Such cylindrical preparations maintain normal vessel geometry and also permit correlation of mechanical phenomena with transmural pressure. These studies s...

journal_title：Annals of biomedical engineering

authors： Dobrin PB

更新日期：1984-01-01 00:00:00

abstract：:Therapeutic irradiation is commonly used in the treatment of malignant brain tumors and has the potential to cause severe injury to normal tissues adjacent to a lesion. Computed tomography (CT) can be used not only to visualize tissue damage but to monitor the development of a lesion using advanced quantitative CT tec...

journal_title：Annals of biomedical engineering

authors： Russell LB,Fike JR,Cann CE,Süsskind C

更新日期：1984-01-01 00:00:00

abstract：:High-frequency ventilation (HFV) has not one but several histories. Proceeding along largely independent pathways are techniques using frequencies of 1-5 Hz and techniques using 10-40 Hz, the former being introduced by Sjostrand in 1971, the latter by Lunkenheimer in 1972. It was nearly ten years before it was recogni...

journal_title：Annals of biomedical engineering

authors： Bryan AC

更新日期：1984-01-01 00:00:00

abstract：:The objective of this paper is to review the theoretical basis and clinical application of electrical impedance plethysmography in the noninvasive evaluation of peripheral arterial and venous disease. Theoretical, experimental and clinical studies have not demonstrated a direct relationship between electrical impedanc...

journal_title：Annals of biomedical engineering

authors： Zuech PE,Cobbold RS,Johnston KW,Kassam M

更新日期：1984-01-01 00:00:00

abstract：:A comparison was made between turbulence calculated by subtracting an ensemble average from the instantaneous velocity and calculations made with a high pass digital filter. Velocity was measured with a laser Doppler anemometer in vitro in the region of a normal porcine aortic valve and in patients with a hot film ane...

journal_title：Annals of biomedical engineering

authors： Walburn FJ,Sabbah HN,Stein PD

更新日期：1983-01-01 00:00:00

abstract：:Instrumentation systems for breath-to-breath analysis of respiratory gas exchange have been faulted by phase lags between various flow and composition signals and by difficulties in gathering and processing large amounts of data. The system described here represents an attempt to overcome these problems. Phase delays ...

journal_title：Annals of biomedical engineering

authors： Sodal IE,Swanson GD,Micco AJ,Sprague F,Ellis DG

更新日期：1983-01-01 00:00:00

abstract：:The appropriateness of integrated information systems to the description of integrated biological systems is discussed. An integrated information system in the physiology of the regulation of respiration is argued to be a structural mathematical model of the system and the relational data base, which it can compute. I...

journal_title：Annals of biomedical engineering

authors： Yamamoto WS

更新日期：1983-01-01 00:00:00

abstract：:Measurement of the instantaneous pressure-volume relationship of the left ventricle is fundamental to the study of ventricular mechanics. In order to effectively investigate this relationship, it is necessary to vary and control the time course of ventricular volume change in a variety of prescribed manners. In the pa...

journal_title：Annals of biomedical engineering

authors： Sunagawa K,Lim KO,Burkhoff D,Sagawa K

更新日期：1982-01-01 00:00:00